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Society for Systems Biology & Translational Research

( Regn. No. S/2L/No. 10387 of 2013-14 of West Bengal Act XXVI of 1961 )
( 12A Certificate Memo No. CIT(E)/10E/745/2017-18/18-19/S-0042/0344-46 )
( 80G Order No. ITBA/EXM/S/80G/2018-19/1014606278(1) dated 27/12/2018 )
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utpal basu
9432322702 | utpal_basu@yahoo.com
10 N. S. Road, Harinavi, Kolkata 700148
Saturday, 13th October, 1973
Same as Present Address
Indian
Male
Ph.D.
Professor, Dept. Mol. Biol. & Biotech.
University of Kalyani

Skeletal Muscle Development

  • Gene Therapy by Viral Vector
  • Expression of utrophin gene expression


Postdoctoral Fellow, Department of Physiology and Pennsylvania Muscle Institute, University of Pennsylvania School of Medicine, USA





  1. Ghosh T, Basu U. Cis-Acting Sequence Elements and Upstream Open Reading Frame in Mouse Utrophin-A 5'-UTR Repress Cap-dependent Translation. PloS One 10, e0134809 (2015).
  2. Ghosh U, Bose S, Ghosh T, Bandyopadhyay TK, Basu U. A Monophasic Solution for Isolation of RNA Devoid of Polymerase Chain Reaction-detectable Genomic DNA Contamination. Anal Biochem 477, 50-2 (2015).
  3. Basu U, Lozynska O, Moorwood C, Patel G, Wilton S.D, Khurana T.S. Translational Regulation of Utrophin by miRNAs. PloS One 6, e29376 (2011). 
  4. Baby SM, Bogdanovich S, Willmann G, Basu U, Lozynska O, Khurana T.S. Differential Expression of Utrophin-A and -B Promoters in the Central Nervous System (CNS) of Normal and Dystrophic mdx Mice. Brain Pathol 20, 323-42 (2010). 
  5. Basu U, Gyrd-Hansen M, Baby S.M, Krag T.O.B, Jensen C, Frodin M, Khurana T.S. Heregulin-induced epigenetic regulation of the utrophin Promoter. FEBS Letter 581, 4153-4158 (2007).
  6. Perkins K.J, Basu U, Budak M, Ketterer C, Baby S.M., Lozynska O, Lunde J.A, Jasmin B.J, Rubinstein N.A and Khurana T.S. ERF silences extra-synaptic utrophin by N-box mediated repression in skeletal muscle. Molecular Biology of the Cell 18, 2864-2872 (2007). 
  7. Basu U. and Banerjee S. An engineered EBV vector expressing human factor VIII and von Willebrand factor in cultured B-cells. Journal of Gene Medicine 6, 760-768 (2004).





  • National Scholarship (1992-95)
  • National Scholarship (1995-97)
  • Institutional Fellowship (1997-2004) (for Ph.D.) of Saha Institute of Nuclear Physics in Biophysical Sciences
  • Junior Research Fellowship (Council of Scientific & Industrial Research, Govt. of India): 1998 (declined)
  • Award: Best oral presentation by young scientists in XXVI All India Cell Biology Conference and Symposium, 2002. Advance Centre for Treatment Research Education and Cancer. Mumbai, INDIA.


  1. Identification and characterization of proteins interacting with utrophin-A IRES. DBT funded 3 years project. Rs. 38,30,000/- (2011).
  2. Study of IRES of mouse utrophin-A mRNA in different cell lines and S. cerevisiae. UGC funded 2 years project. Rs. 1,90,000/- (2011).
  3. Molecular characterization of IRES of utrophin-A mRNA. DST funded 3 years project. Rs. 16, 71,000/- (2009).


INVITED LECTURE:

Basu U. Regulation of utrophin expression & its therapeutic implications in Duchenne Muscular Dystrophy. UGC sponsored State Level Seminar on “Biochemical Diversity Encompassing Advanced Sustainable Development” held on 14 December 2013 at Vivekananda College, Kolkata 700063



Reviewer: PLoS One



PATENT:

Moorwood C, Basu U, Patel G, Lozynska O, Khurana T.S. Methods for enhancing utrophin production via inhibition of microRNA, University of Pennsylvania.


Member Since : 25th January, 2014  | Profile Last Updated On : 07th March, 2023 9:49 PM
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